Figure 1. Simulated chemical concentration and electric field distribution of the dual-field chip.

(A) The geometry and EGF concentration distribution in the dual field chip. Note that even for a small protein like EGF, only a small portion of it would be transported and create localized chemical gradient. Regions for cell observation are outlined in yellow dash lines. (B) The dcEF strength distribution in the dual field chip. Note that cell electrotaxis and random migration (control) with and without EF can be studied in a single chip. Regions with uniform EF distribution are outlined in red dash lines.