Table 2. Aggressive phenotype disease according TGFBR2-875G>A polymorphism.
|
Gleason Score
|
OR | 95% CI | P | ||
|---|---|---|---|---|---|
| TGFBR2-875G>A | <8 | ≥8 | |||
| AA/AG | 274 (0.39) | 55 (0.30) | |||
| GG | 431 (0.61) | 131 (0.70) | 1.51 | 1.07-2.16 | 0.019 |
| Stage | |||||
| TGFBR2-875G>A | Localized (T1-T2 stages) | Advanced (T3- T4, N and M+) | |||
| AA/AG | 162 (0.39) | 166 (0.35) | |||
| GG | 252 (0.61) | 310 (0.65) | 1.20 | 0.91-1.58 | 0.189 |
| Hormone resistance | |||||
| TGFBR2-875G>A | No | Yes | |||
| AA/AG | 133 (0.40) | 55 (0.32) | |||
| GG | 196 (0.60) | 114 (0.68) | 1.41 | 0.95-2.08 | 0.084 |
OR, odds ratio; 95% CI, 95% confidence interval; univariate analysis