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. 2013 Aug 9;8(8):e70783. doi: 10.1371/journal.pone.0070783

Figure 1. Effects of H. hepaticus infection on MIT vs. MHH mice.

Figure 1

Intestinal inflammation induced by H. hepaticus infection in C57BL/6J Il10−/− mice reared in MIT and MHH SPF facilities. A, histological sections (H&E stain); B, Histological sections of cecum were scored separately for inflammation, epithelial defects, edema, crypt atrophy, hyperplasia and dysplasia on a scale of 0 to 4. The scores from all the different parameters were added and represented as Typhlitis Index scores as described in Burich et al. [29]. P values according to nonparametric Mann-Whitney test, **<0.005.