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Four observers’ contours of malignant pleural mesothelioma on the follow-up CT scan of the patient in Fig. 1. All observers were shown the baseline scan contour in Fig. 1e as a reference for the construction of their follow-up scan contours. Note that not all observers selected the same follow-up scan section on which to construct the tumor contour. The corresponding areas of the four measurements are (a) 3813, (b) 3659, (c) 3853, and (d) 3139 mm2.
