Fig. 1.

Effects of murine 3K3A-APC late multiple dose therapy on functional recovery within 14 days of permanent dMCAO. Forelimb use asymmetry test (A) and foot-fault test (B) were performed within 14 days after stroke in F2r^+/+ C57Bl6 mice treated with vehicle (saline) or multiple dose 3K3A-APC (0.8 mg/kg intraperiotoneally) administered at 12 h, 1, 3, 5 and 7 days after onset of ischemia. Mean±SEM, n = 10 mice/group for functional tests in A–B within 7 days; n = 5 mice/group for functional tests at 14 days. *, **P<0.05.