Fig. 9.
Effects of 5,14-HEDGE and 20-HEDE on survival 72 h after saline (vehicle) (4 ml/kg, i.p.) or LPS (10 mg/kg, i.p.) injection to conscious mice. 5,14-HEDGE (30 mg/kg, s.c.) and/or 20-HEDE (30 mg/kg, s.c.) were given 1 h after administration of saline or LPS. Data are obtained from 20–50 observations. *Significant difference from the corresponding value seen in rats treated with saline (p < 0.05). #Significant difference from the corresponding value seen in the rats treated with LPS (p < 0.05).