Table 3.
Group(s) | Region | BA | Side | k | t | MNI-coordinates | ||
---|---|---|---|---|---|---|---|---|
x | y | z | ||||||
Moral vs BL | ||||||||
HC | Precuneus | BA7 | L + R | 236 | 12.24 | −3 | −55 | 34 |
Angular gyrus | BA39 | L + R | 301 | 10.80 | −48 | −64 | 22 | |
Angular gyrus | BA39 | R | 31 | 5.59 | 48 | −58 | 22 | |
Medial frontal gyrus | L + R | 536 | 10.87 | 0 | 50 | 22 | ||
ASD | Medial frontal gyrus | BA10 | L + R | 667 | 10.16 | 3 | 53 | 25 |
Middle frontal gyrus | L | 50 | 6.01 | −24 | 29 | 40 | ||
Middle frontal gyrus | R | 34 | 5.91 | 30 | 29 | 46 | ||
Precuneus | BA7 | L + R | 319 | 9.46 | −3 | −55 | 37 | |
Angular gyrus | BA39 | L | 196 | 8.03 | −45 | −61 | 25 | |
Inferior temporal gyrus | BA20 | L | 34 | 5.58 | −54 | −4 | −35 | |
Supramarginal gyrus | R | 83 | 6.55 | 60 | −55 | 28 | ||
SE vs BL | ||||||||
HC | Precuneus | BA7 | L | 313 | 14.65 | −3 | −55 | 34 |
Middle temporal gyrus | L | 258 | 11.51 | −48 | −64 | 25 | ||
Medial frontal gyrus | L | 377 | 9.18 | −6 | 50 | 25 | ||
Medial frontal gyrus | BA10 | L + R | 42 | 8.00 | −3 | 56 | 5 | |
Middle frontal gyrus | L | 31 | 6.29 | −27 | 29 | 25 | ||
ASD | Precuneus | BA7 | L + R | 394 | 10.22 | −3 | −55 | 34 |
Medial frontal gyrus | L + R | 463 | 9.25 | −9 | 50 | 19 | ||
Middle frontal gyrus | L | 27 | 5.75 | −24 | 29 | 40 | ||
Angular gyrus | BA39 | L | 174 | 8.11 | −42 | −61 | 25 | |
Precentral gyrus | L | 22 | 5.66 | −57 | −7 | −29 | ||
IND vs BL | ||||||||
HC | Medial frontal gyrus | BA10 | L + R | 27 | 10.33 | 27 | −79 | −35 |
Medial frontal gyrus | BA9 | L + R | 499 | 7.50 | 3 | 50 | 22 | |
Angular gyrus | BA39 | L + R | 261 | 7.03 | −48 | −64 | 22 | |
Angular gyrus | BA39 | R | 70 | 5.62 | 60 | −49 | 28 | |
Precuneus | BA7 | L + R | 75 | 6.06 | −3 | −55 | 34 | |
ASD | Medial frontal gyrus | BA2 | L + R | 561 | 10.17 | 3 | 53 | 25 |
Middle frontal gyrus | BA8 | L | 31 | 5.95 | −27 | 29 | 43 | |
Middle frontal gyrus | R | 28 | 6.65 | 30 | 29 | 43 | ||
Middle temporal gyrus | R | 27 | 6.63 | 60 | −19 | −14 | ||
Angular gyrus | BA39 | L | 93 | 6.18 | −45 | −61 | 25 | |
Supramarginal gyrus | R | 109 | 6.62 | 60 | −55 | 28 | ||
Precuneus | BA7 | L + R | 94 | 6.51 | −3 | −55 | 37 | |
Uvula | R | 32 | 5.84 | 30 | −82 | −35 | ||
Uvula | L | 59 | 5.55 | −24 | −82 | −32 | ||
SE vs IND | ||||||||
HC | Posterior cingulate cortex | L + R | 207 | 7.72 | 0 | −58 | 28 | |
ASD | Posterior cingulate cortex | BA 31 | L | 67 | 5.89 | −3 | −52 | 28 |
IND vs SE | ||||||||
HC | Temporo-parietal junction | L | 20 | 5.36 | −57 | −43 | 31 | |
Inferior frontal gyrus | BA 47 | R | 25 | 5.35 | 51 | 35 | −5 | |
Lingual gyrus | R | 81 | 5.42 | 12 | −73 | −2 | ||
Middle temporal gyrus | R | 98 | 6.60 | 57 | −25 | −14 | ||
Declive | L | 45 | 7.37 | −21 | −79 | −22 | ||
ASD | N.S. |
Whole-brain analyses; flexible-factorial ANOVA; threshold = P < 0.05 FWE corrected, extent threshold = 20 voxels; Moral = combined SE and IND dilemmas, SE = social-ethical dilemmas, IND = individual gain vs collective losses dilemmas, BL = (weighted) high-level baseline; ASD = patients with autism spectrum disorder; HC = Healthy controls; L = left; R = right, BA = Brodmann’s Area; N.S. = not significant.