Table 2.

Motor function test with rotarod treadmill in two groups (x±s, s)

Group	n	Time of fall off
		−1 d I	−1 d II	3 h of 0 d	6 h of 0 d	1 d I	1 d II
Control
15 r/min	4	57.89±2.2	58.33±0.33	54.33±6.89	58.33±3.33	58.75±1.73	59.92±0.17
45 r/min	4	44.11±14.11	50.17±9.13	51.50±7.38	52.25±7.34	48.17±9.25	47.67±12.76
HLXLD
15 r/min	4	60.00±0.00	59.91±0.16	60.00±0.00	58.58±2.83	58.58±2.83	59.92±1.67
45 r/min	4	56.13±4.95	54.50±6.56	53.42±7.6	53.83±7.20	52.83±11.25	52.50±8.69

Group	n	Time of fall off
		3 d I	3 d II	5 d I	5 d II	7 d I	7 d II
Control
15 r/min	4	59.92±0.17	59.33±1.33	56.08±4.57	56.58±3.95	60.00±0.00	56.67±5.23
45 r/min	4	49.75±7.59	51.58±10.21	46.83±10.54	46.92±9.17	50.75±7.05	48.08±13.79
HLXLD
15 r/min	4	59.08±1.83	57.50±3.79	56.17±4.46	58.33±3.33	59.00±2.00	58.33±3.33
45 r/min	4	52.25±10.27	48.67±9.36	50.42±11.07	51.83±9.46	46.33±12.13	50.75±7.77

Notes: −1 d, the time point 1 day before CFA injection used in a inflammation rat model; 3 h of 0 d, 3 hours after HLXLD or vehicle administration; 6 h of 0 d, 6 hours after HLXLD or vehicle administration; 1 d, 3 d, 5 d and 7 d: the time points 1, 3, 5 or 7 days after CFA injection used in a inflammation rat model; I, immediate before HLXLD or vehicle administration; II, 1 hour after HLXLD or vehicle administration. There were no significant changes in motor function after HLXLD administration for 9 consecutive days at rotarod treadmill speed of 15 r/min (F=0.99, P=0.49) or 45 r/min (F=0.30, P=0.99).