FIG. 6.

Nuclear magnetic resonance structure of Δ76 Tb1-C-Grx1. (A) Superposition of the backbone of the 20 conformers with the best CYANA target function, refined with Amber. Active-site residues (104–107, yellow), cis-proline-containing loop (residues 141–146, magenta), residues involved in the formation of the conserved β-bulge (148, 155, and 156, light blue), and residues from C-terminus (178–182, cyan) are highlighted. The positions of Cys104 and Cys181 are indicated with black arrows. (B) Ribbon representation showing secondary-structure elements. The program MOLMOL was used to prepare these figures To see this illustration in color, the reader is referred to the web version of this article at www.liebertpub.com/ars