Table 5.

Pathologic Features Stratified by Cytologic Diagnosis and Papillary Carcinoma Subtype

			Cytologic Diagnosis
Papillary Subtype			Malignant	Suspicious for malignancy	Follicular Neoplasm	AUS	Total
FV	T Stage	T1	26	80	16	28	150
		T2	14	44	18	11	87
		T3	6	11	4	5	26
		T4	0	1	0	0	1
	Total		46	136	38	44	264
CV	T Stage	T1	42	16	7	7	72
		T2	19	9	4	1	33
		T3	19	3	1	0	23
		T4	1	0	0	0	1
	Total		81	28	12	8	129
High-risk	T Stage	T1	15	10	0	0	25
		T2	6	1	1	0	8
		T3	37	5	1	0	43
		T4	3	2	0	0	5
	Total		61	18	2	0	81
FV	N Stage	N0	24	67	14	23	128
		N1	4	4	1	0	9
	Total		28	71	15	23	137
CV*	N Stage	N0	31	20	6	3	60
		N1	31	1	0	1	33
	Total		62	21	6	4	93
High-risk	N Stage	N0	23	9	1	0	33
		N1	29	4	0	0	33
	Total		52	13	1	0	66
FV*	LVI	Absent	37	122	34	43	236
		Present	9	14	4	1	28
	Total		46	136	38	44	264
CV*	LVI	Absent	46	24	8	8	86
		Present	35	4	4	0	43
	Total		81	28	12	8	129
High-risk *	LVI	Absent	12	10	2	0	24
		Present	49	8	0	0	57
	Total		61	18	2	0	81
FV	ETE	Absent	42	132	38	43	255
		Present	4	4	0	1	9
	Total		46	136	38	44	264
CV*	ETE	Absent	62	26	12	8	108
		Present	19	2	0	0	21
	Total		81	28	12	8	129
High-risk *	ETE	Absent	21	14	2	0	37
		Present	40	4	0	0	44
	Total		61	18	2	0	81
FV	Recur/Met?	No	45	136	38	44	263
		Yes	1	0	0	0	1
	Total		46	136	38	44	264
CV	Recur/Met?	No	74	28	12	8	122
		Yes	7	0	0	0	7
	Total		81	28	12	8	129
High-risk	Recur/Met?	No	53	18	2	0	73
		Yes	8	0	0	0	8
	Total		61	18	2	0	81

Abbreviations: FV – follicular variant; CV – conventional variant; LVI – lymphovascular invasion; ETE – extrathyroidal extension; Recur/Met? – local recurrence and/or metastasis;

NS – not significant

^*Asterisk denotes statistical significance

T stage: FV (P=0.58, NS), CV (P=0.37, NS), High-risk (P=0.08, NS)

N stage: FV (P=0.15, NS), CV (P<0.001), High-risk (P=0.13, NS)

LVI: FV (P=0.05), CV (P=0.002), High-risk (P=0.001)

ETE: FV (P=0.13, NS), CV (P=.008), High-risk (P=0.001)

Recur/Met?: FV (P=0.32, NS), CV (P=0.08, NS), High-risk (P=0.09, NS)