Table 1.
Phenotype of different murine stem cell populations
| Oct4 | Nanog | Stella (DPPA3) |
Vasa | SSEA-1 | CXCR4 | CD45 | Sca-1 | c-kit | LIFR | |
|---|---|---|---|---|---|---|---|---|---|---|
| VSEL | + | + | + | + | + | + | − | + | +/− | + |
| ESC | + | + | + | + | + | − | − | − | + | + |
| PGC | + | + | + | + | + | + | − | ? | + | + |
| HSPC | − | − | − | − | − | + | + | + | + | ? |
Gene expression levels (Oct-4, Nanog, Stella, Vasa) or expression levels of cell surface markers (SSEA-1, CXCR4, CD45, Sca-1, c-kit, LIFR) on murine cell populations. VSEL = very small embryonic like cells, ESC= embryonic stem cells, PGC = primordial germ cells, HSPC = hematopoietic stem and progenitor cells. + = positive, − = low or negative, +−= expressed on a fraction of the cells, ?= No literature available. References: (Kucia et al. 2006), (Gu et al. 2010; Muramatsu and Muramatsu 2004; Saga 2008). C-Kit on VSEL’s: Ratajczak and Kassmer, unpublished observations.