Table 4.
Carotid Arterial Stiffness Measurements
ET | CT | P-Value | |||||
---|---|---|---|---|---|---|---|
Baseline | 8 Week | Final | Baseline | 8 Week | Final | ||
N | 24 | 20 | 23 | 24 | 21 | 20 | |
Main measure | |||||||
AD (×10-3 mm*mmHg-1) | 1.07 ± 0.50 | 1.14 ± 0.70 | 0.97 ± 0.56 | 0.89 ± 0.35 | 0.97 ± 0.51 | 1.07 ± 0.34 | 0.65 |
Other measures | |||||||
AC (×10-3 mm*mmHg-1) | 65.1 ± 20.9 | 76.8 ± 64.7 | 58.8 ± 32.8 | 51.6 ± 23.4 | 51.3 ± 17.4 | 61.7 ± 21.1 | 0.64* |
PEM (kPa) | 232 ± 150 | 223 ± 181 | 224 ± 198 | 242 ± 109 | 235 ± 147 | 242 ± 111 | 0.41* |
YEM (kPa) | 1504 ± 1160 | 1302 ± 1089 | 1427 ± 1385 | 1209 ± 642 | 1195 ± 864 | 1128 ± 648 | 0.82* |
Beta Index | 16.11 ± 9.36 | 16.45 ± 12.46 | 15.77 ± 12.66 | 16.91 ± 7.61 | 16.82 ± 10.46 | 16.58 ± 7.16 | 0.50* |
Pulse pressure | |||||||
PP (mmHg) | 70 ± 16 | 65 ± 12 | 62 ± 13 | 73 ± 17 | 67 ± 12 | 68 ± 12 | 0.24 |
Arterial dimensions | |||||||
IMT (mm) | 0.74 ± 0.08 | 0.75 ± 0.09 | 0.76 ± 0.11 | 0.84 ± 0.14 | 0.82 ± 0.10 | 0.84 ± 0.10 | 0.30 |
SAD (mm) | 8.33 ± 1.12 | 8.31 ± 1.18 | 8.45 ± 1.20 | 8.26 ± 0.92 | 8.11 ± 0.89 | 8.35 ± 0.97 | 0.47 |
DAD (mm) | 7.93 ± 1.15 | 7.90 ± 1.17 | 8.01 ± 1.19 | 7.89 ± 0.90 | 7.72 ± 0.89 | 8.00 ± 0.96 | 0.52 |
SLD (mm) | 6.98 ± 1.19 | 7.02 ± 1.29 | 6.83 ± 1.02 | 6.63 ± 1.02 | 6.46 ± 0.88 | 6.53 ± 0.87 | 0.90 |
DLD (mm) | 6.53 ± 1.22 | 6.57 ± 1.17 | 6.43 ± 1.02 | 6.21 ± 0.94 | 6.08 ± 0.91 | 6.09 ± 0.80 | 0.72 |
ADC (mm) | 0.40 ± 0.17 | 0.41 ± 0.20 | 0.44 ± 0.24 | 0.38 ± 0.16 | 0.39 ± 0.27 | 0.35 ± 0.14 | 0.49* |
Data represent means ± SD; p-value represents comparison of least square means of the main effect across the follow-up visits following adjustment for baseline values. Abbreviations: AD: arterial distensibility; AC: arterial compliance; PEM: Peterson's elastic modulus; YEM: Young's elastic modulus; kPa: kilopascals; PP: pulse pressure; IMT: mean wall intimal medial thickness; SAD: systolic arterial diameter; DAD: diastolic arterial diameter; SLD: systolic lumen diameter; DLD: diastolic lumen diameter; ADC: arterial diameter change during cardiac cycle.
p-value is shown following logarithmic transformation of this highly skewed variable.