Table 2. Description of Kinome Render formatting syntax language commands.

Command	Description	Value
at (value)	Specifies the kinase to which to assign the annotation	Name (see Table S1) i.e., Abl
color (value)	Sets the color of the annotations	RGB values between 0 and 1 i.e., 1 0.67 0.5 or one of the predefined color (black, red, green, blue, yellow, magenta, cyan, orange, pink, grey)
scale (value)	Sets the size of the annotations	Integer (default 10)
text (value)	Prints a string of text	String (max. 25 characters, see Table 1 for special characters)
circle circle-filled circle-lined	Draws a circle Draws a color-filled circle Draws a color-filled circle with a black outline	N.A.
polygon (value) polygon-filled (value) polygon-lined (value)	Draws a polygon of (value) sides Draws a color-filled polygon Draws a color-filled polygon with a black outline	integer (e.g.,: polygon 4 will draw a square)
boxed	Encloses the annotation in a box	N.A.
underlined	Underlines the annotation	N.A.
remainder	Prints the names of all non-annotated kinases (add this command once at the last line of your file)	N.A.
legend	Declares that the following lines describe the legend	N.A.
space	Adds a trailing space in an element of the legend	N.A.
next-line	Jumps to the next line in the legend	N.A
legendBox	Inserts a box around the legend; Must be placed in the last line of the legend section