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. Author manuscript; available in PMC: 2014 Jul 3.
Published in final edited form as: J Am Chem Soc. 2013 Jun 20;135(26):9760ā€“9767. doi: 10.1021/ja401692t

Figure 2.

Figure 2

Sequence specificity of VH1 toward pS/pT peptides. (A) Preferred class I substrates selected from the N-terminal library (X5pS/pT). (B) Preferred class II substrates selected from the N-terminal library. (C) Preferred substrates selected from the C-terminal library (pS/pTX5). The histograms represent the amino acids identified at each position from Pāˆ’5 to P+5 (z-axis). Frequency of occurrence on the y-axis represents the percentage of selected sequences that contained a particular amino acid at a certain position. M, Nle; U, Abu.