Table 1.
Patients' characteristics n (%)
| Thiopurines (n = 429) | No thiopurines (n = 383) | P value | |
| Age of diagnosis of IBD (yr) | 30.85 | 40.13 | < 0.001 |
| Sex | |||
| Female | 192 | 178 | > 0.050 |
| Male | 237 | 205 | > 0.050 |
| Ulcerative colitis1 | n = 130 | n = 263 | < 0.001 |
| Extension | |||
| E1 | 5 (3.85) | 51 (19.4) | |
| E2 | 42 (32.3) | 103 (39.2) | |
| E3 | 83 (63.85) | 109 (41.4) | |
| Severity | |||
| S1 | 51 (39.2) | 150 (57) | |
| S2 | 58 (44.6) | 102 (38.8) | |
| S3 | 21 (16.2) | 11 (4.2) | |
| Crohn's disease2 | n = 299 | n = 120 | < 0.001 |
| Age of diagnosis (yr) | |||
| A1 | 33 (11) | 6 (5) | |
| A2 | 214 (71.6) | 68 (56.7) | |
| A3 | 52 (17.4) | 46 (38.3) | |
| Location | |||
| L1 | 137 (45.8) | 46 (38.3) | |
| L2 | 54 (18) | 34 (28.3) | |
| L3 | 96 (32.1) | 39 (32.5) | |
| L4 | 12 (4.1) | 1 (0.8) | |
| Behaviour | |||
| B1 | 155 (51.8) | 105 (87.5) | |
| B2 | 55 (18.4) | 10 (8.3) | |
| B3 | 89 (29.8) | 5 (4.2) | |
| P | 73 (24.4) | 15 (12.5) | |
| Neoplasms | n = 17 | n = 31 | 0.013 |
1
Patients with ulcerative colitis treated with thiopurines had more severity and disease extension;
2
Patients with Chron's disease treated with thiopurines more usually had ileal or ileocholic location and an inflammatory or penetrating behaviour; Patients under thiopurine treatment had a lower age at diagnosis. IBD: Inflammatory bowel disease.