Table 1.
Study design1 | Cohort and disease | Number of families | Number of individuals | Women |
Case control study | Healthy unrelated controls | 333 | 162 | |
Swedish IBD families | 191 | |||
IBD | 347 | 157 | ||
CD | 150 | 69 | ||
UC | 166 | 71 | ||
IBD-U | 31 | 17 | ||
Family based approach | Non-Swedish families | 463 | ||
IBD | 715 | 398 | ||
CD | 528 | 297 | ||
UC | 151 | 83 | ||
IBD-U | 36 | 18 |
Including Claudin (CLDN)1, CLDN2, CLDN4. IBD: Inflammatory bowel disease; CD: Crohn’s disease; UC: Ulcerative colitis; IBD-U: Unclassified colitis.