Table 1.

Summary of best practices from 5th Annual Clinical Research Management Workshop

CTSA Site	Target	Best Practice	Effect
University of Washington	Overall assessment of research hospital	Introduce “Toyota” management	• Reduced mean IRB approval from 44 to 13 days • Reduced concurrent protocol processing from 370 to 69 studies under review. • Increased research visits to 9% of total visits • Decreased “problem score” from 58 to 35
Harvard University	Study approval time	Streamline processing, eliminate useless steps, parallel processing, electronic workflow; 524 protocols reviewed electronic scheduling	Study Approval Time reduced by 56%
CTSA Consortium van Dalfsen	Time to first participant Enrolled in multisite national study	Compare best and worst nationally: Key success factors were • Shared leadership (PI/manager) • Clear, shared process for research • Regular, effective communication • Business‐like approach (financial systems and practices) • Hiring the right people	Best quartile–activated studies soonest, enrolled 16–40% of participants Worst quartile–activated studies latest, enrolled 0–15% of participants.
University of Michigan	Increase research participation	Research volunteer registry based on preliminary study of perceptions (investigators and participants) • Teach participants about research • Increase awareness of studies • Increased access to registration • Electronic management	• Increased participants in system by 39% (6,500 → 9,300) • Volunteer registry 10,700 participants (increased 224%)
CTSA Consortium Drezner, Cobb	IRB approval time	2009 Study of IRB processing (33 sites, 425 protocols) vs. 2011 Study (43 sites, 1,401 protocols).	Reduced median approval time from 64 days to 54 days