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. Author manuscript; available in PMC: 2013 Nov 21.
Published in final edited form as: J Am Chem Soc. 2012 Nov 8;134(46):19223–19233. doi: 10.1021/ja3090687

Figure 6.

Figure 6

ICP-MS assay for nuclear and mitochondrial rhodium accumulation. HCT116O cells were treated with 10 μM of each rhodium complex (except [Rh(DIP)2(chrysi)]3+, which was administered at 2 μM) for 24 h. The cells were harvested by trypsinization and appropriate organelle isolation procedures performed. The mitochondrial rhodium counts were normalized to protein content, which was determined by a BCA assay. The nuclear rhodium numbers were normalized to number of nuclei.