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Published in final edited form as: Clin Immunol. 2009 May 7;132(2):203–214. doi: 10.1016/j.clim.2009.03.530

Consensus sequences of 82 extended DR-B-A haplotype groups. Consensus sequences from 82 DR-B-A haplotype groups are shown, organized by different criteria in each panel. In this graph, each column represents the consensus sequence from one haplotype group, and each row one SNP. 2837 SNPs are shown for each consensus sequence. Haplotype groups are compared to the 3.8.1c consensus sequence shown on the far left in panel A (also labeled with an asterisk (*) in panels B, C and D). Yellow boxes show that the allele matches that of the 3.8.1c, whereas blue represents the opposite allele. The telomeric end of the MHC is at the top of the graph. (A) Haplotype consensus sequences are in the same order as Figure 1 (numbers at bottom of picture are defined in Supplementary Table 1). (B) Haplotype consensus sequences are grouped on the x-axis by HLA-DR alleles, followed by HLA-B and HLA-A alleles respectively. (C) Haplotype consensus sequences are grouped on the x-axis by HLA-B alleles, followed by HLA-A and HLA-DR alleles respectively. (D) Haplotype consensus sequences are grouped on the x-axis by HLA-A alleles, followed by HLA-B and HLA-DR alleles respectively.

Consensus sequences of 82 extended DR-B-A haplotype groups. Consensus sequences from 82 DR-B-A haplotype groups are shown, organized by different criteria in each panel. In this graph, each column represents the consensus sequence from one haplotype group, and each row one SNP. 2837 SNPs are shown for each consensus sequence. Haplotype groups are compared to the 3.8.1c consensus sequence shown on the far left in panel A (also labeled with an asterisk (*) in panels B, C and D). Yellow boxes show that the allele matches that of the 3.8.1c, whereas blue represents the opposite allele. The telomeric end of the MHC is at the top of the graph. (A) Haplotype consensus sequences are in the same order as Figure 1 (numbers at bottom of picture are defined in Supplementary Table 1). (B) Haplotype consensus sequences are grouped on the x-axis by HLA-DR alleles, followed by HLA-B and HLA-A alleles respectively. (C) Haplotype consensus sequences are grouped on the x-axis by HLA-B alleles, followed by HLA-A and HLA-DR alleles respectively. (D) Haplotype consensus sequences are grouped on the x-axis by HLA-A alleles, followed by HLA-B and HLA-DR alleles respectively.