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. Author manuscript; available in PMC: 2013 Aug 12.
Published in final edited form as: Biol Psychiatry. 2010 Dec 8;69(5):415–423. doi: 10.1016/j.biopsych.2010.10.003

Table 3.

Within-Group Activations and Between-Group Differences in Activation for the Self-Reflection (SR) Versus Affect-Labeling (AL) Contrast in the Cortical Surface–Based Analysis

Region BA Area (mm2) Tal (x, y, z) p Value
Control Group (n = 17)
 L Medial Frontal and Anterior Cingulate Gyri 32/10 2443 −11,44,2 .00003
 L Medial and Middle Frontal Gyri 10/9 585 −24,50, 12 .0007
 L Middle Frontal Gyrus 9 224 −21,36,28 .0002
 R Medial Frontal Gyrus 10 1949 10,52,3 .00008
 L Posterior Cingulate Gyrus 23/31 831 −9, −56,28 .0001
 R Posterior Cingulate Gyrus 23 428 8, −56,20 .001
Schizophrenia Group (n =18)
 L Anterior Cingulate Gyrus 32 1792 −6, 32, −6 .00009
 R Anterior Cingulate Gyrus 24/32 1815 7,31, −3 .00005
 R middle cingulate gyrus 23/24 458 5,−16,31 .001
 L Posterior Cingulate Gyrus/RSC 23/30 2266 −8, −51,20 .0001
 R Posterior Cingulate Gyrus/RSC 23/30 575 8, −50,22 .0007
Control > Schizophrenia
 R Medial Orbitofrontal Gyrus 10/11 116 8,42, −15 .005
Schizophrenia > Control
 L Mid/Posterior Cingulate Gyrus 23/31 236 −6,−30, 34 .002
 R Mid/Posterior Cingulate Gyrus 23 321 5, −21,31/0, −16,24 .002

Location and size of clusters of vertices that showed significant SR>AL activation for the controls (n=17) and the patients with schizophrenia (n=18), with the Talairach coordinates and p value for the local p minimum for each cluster. There were no loci that showed significantly greater activation for the AL condition, relative to SR. Loci which showed significantly more activation in the controls compared with the patients and those that showed more activation in the patients compared to the controls are also listed.

AL, affect labeling; BA, Brodmann area; L, left; R, right; RSC, retrosplenial cortex; SR, self-reflection; Tal, Talairach coordinates.