Table 2.

Coupled solution-based and structure-based techniques to analyze PLI

First author/reference	Description	Year
Alegre-Cebollada [49]	Binding of Sticholysin II Toxin and its mutants to sphingomyelin/DOPC/Cholesterol-containing liposomes studied by ITC and structural changes upon lipid binding by FTIR	2008
Shao [50]	Binding of Lactadherin C2 Domain to liposomes containing phosphatidylserine by FRET and flow cytometry and structural determination of lipid binding sites by X-ray crystallography	2008
Erlmann [51]	Binding of Deleted in Liver Cancer 1 (DLC1) to liposomes containing phosphatidylinositol-4,5-bisphosphate by liposome sedimentation assay and FRET	2009
Hughes [23]	Binding of Phospholamban (PLM1–23) to phospholipids by ITC and NMR	2009
Jobichen [52]	Binding of GrIR (global regulator of LEE repressor) to phospholipids by ITC and structural characterization of lipid binding domain by X-ray crystallography	2009
Marsh [53]	Orientation and Peptide-Lipid Interactions of Alamethicin Incorporated in Phospholipid Membranes by ESR and IR	2009
Mustafa [44]	Binding of serine racemase to liposomes containing phosphatidylinositol (4,5)-bisphosphate (PIP2) by liposome sedimentation assay and fluorescence anisotropy	2009
Qiu [43]	Interaction of β-amyloid (Aβ) peptide with liposomes by FRET and fluorescence anisotropy	2009
Guillén [45]	Binding of Hepatitis C virus protein NS4B to liposomes by fluorescence anisotropy and structural changes upon lipid binding by IR	2010
Tsujita [17]	Identification of acidic phospholipid-binding protein candidates by Nano-LC-MS/MS and confirmation the interactions between acidic phospholipid-binding proteins with lipids by liposome sedimentation assay	2010
D'Errico [29]	Binding of bovine seminal ribonuclease (BS-RNase) to liposomes by ESR and SPR and structural changes by CD	2011
Hughes [54]	Binding of the cytosolic domain of Phospholamban (PLM38–72) to phospholipids by ITC and NMR and structural determination by CD	2011
Hundertmark [26]	Binding of LEA18 (Late embryogenesis abundant 18) protein to liposomes by ITC and structural determination by CD	2011
Kobashigawa [42]	Binding of EEA1 (Early endosome antigen 1) FYVE domain to liposomes containing phosphoinositides by fluorescence anisotropy and NMR	2011
Bhunia [25]	Binding of scaffold protein Ste5 to phospholipids by ITC and structural determination by NMR and CD	2012
Dixon [39]	Binding of IQ motif containing GTPase activating proteins to phosphoinositides by TR-FRET and X-ray crystallography	2012
Hoernke [24]	Binding of cationic pentapeptides to liposomes by ITC and FTIR	2012
Krishnakumari [55]	Binding of peptides corresponding to the carboxyl-terminal region of human-β-defensins-1–3 to liposomes by ITC and fluorescence anisotropy	2012