Skip to main content
. Author manuscript; available in PMC: 2013 Aug 12.
Published in final edited form as: Nat Commun. 2013;4:1528. doi: 10.1038/ncomms2537

Table 1.

Anthropometric, demographic and clinical parameters of the experimental subgroups.

Control Obese Obese-diabetic P-value
n (female/male) (9/10) (11/10) (10/11)
Age (year) 57.8 (54.4–61.2)a 45.9 (42.6–49.1)b 49.8 (46.5–53.1)a,b 2.1 ×10−5*
BMI (kg m−2) 25.7 (23.6–28.0)a 51.4 (47.6–55.5)b 54.0 (50.3–58.0)b 1.3 × 10−18*
CRP (mg l−1) 2.0 (1.4–3.0)a 8.4 (5.9–11.9)b 11.4 (8.2–15.8)b 4.6 × 10−8*
Liver steatosis (%) 2.6 (1.2–4.9)a 19.0 (11.3–31.5)b 34.0 (21.1–54.3)b 2.2 × 10−7*
HbA1c (%) 5.1 (4.8–5.5)a 5.8 (5.5–6.2)a 7.3 (6.9–7.8)b 2.1 × 10−10*
HOMA-IR 1.1 (0.7–1.6)a 4.6 (3.1–6.7)b 8.6 (6.0–12.4)b 1.2 × 10−8*
TG (mg dl−1) 97 (80–118)a 138 (115–165)a 148 (125–174)a 0.008
HDL-C (mg dl−1) 46 (41–51)a,† 42 (38–46)a,† 41 (38–45)a,† 0.419
LDL-C (mg dl−1) 104 (88–123)a 118 (101–138)a 99 (86–114)a 0.236
SBP (mm Hg) 119 (113–125)a 136 (129–142)a 136 (130–142)a 6.6 × 10−4
DBP (mm Hg) 76 (71–82)a 86 (80–93)a 84 (79–89)a 0.070

Abbreviations: CRP, C-reactive protein; DBP, diastolic blood pressure; HDL-C, plasma high-density lipoprotein cholesterol, LDL-C, plasma low-density lipoprotein cholesterol; SBP, systolic blood pressure; TG, total plasma triglycerides.

Estimated means (95% confidence intervals) and P-value for effect of group as determined by ANCOVA. Groups identified by the same superscript letter (a,b) are not significantly different from each other (P≥0.0005).

HDL-C was higher in females compared with males (P = 0.049).

*

Significant after adjustment for multiple testing.

HHS Vulnerability Disclosure