Table 3.

OCD/tic/PANDAS symptomology based on time of surgery.

Neuropsychiatric Symptom		Pre-surgery onset	Post-surgery onset
Total	N	10	22
	Elevated titers, N (%)	8 (80.0)	18 (81.8)
PANDAS	N	6	13
	Elevated titers, N (%)	6 (100.0)	11 (84.6)
OCD	N (%)	6	25
	Elevated titers, N (%)	4 (66.7)	21 (84.0)
	Mean age at onset (yrs)	4.6 ± 1.5	6.4 ± 2.2
	Mean CYBOCS score	19.90	16.50
	Mean age at surgery (yrs)	7.4 ± 3.7	4.1 ± 1.7
	Mean onset to surgery duration (yrs)	−2.8 ± 3.2	2.4 ± 1.9
Tics	N (%)	8	22
	Elevated titers, N (%)	7 (87.5)	17 (77.3)
	Mean age at onset (yrs)	3.6 ± 2.0	6.7 ± 1.9
	Mean YGTSS score	39.00	27.35
	Mean age at surgery (yrs)	6.6 ± 3.7	3.9 ± 1.7
	Mean onset to surgery duration (yrs)	−3.0 ± 3.7	2.9 ± 2.1

Of the 36 participants in the surgery group, age at surgery was not available for 4 youth; titers were not available for one youth. Mean onset to surgery duration was taken as the difference between the time of initial neuropsychiatric symptom onset/diagnosis (i.e., OCD or tics) to the time of first surgical procedure.