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Thermodynamic analysis of VEGF-C binding to VEGFR-3. Calorimetric titrations of VEGF-C to the monomeric VEGFR-3 ECD (D1-7) and its domain deletion mutants D1-2, D1-3 and D1-5 are shown. The enthalpy change (ΔH), dissociation constant (Kd), and stoichiometry (N) of the ITC assays are indicated.
