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. 2013 Jul 22;110(32):12911–12916. doi: 10.1073/pnas.1222041110

Fig. 6.

Fig. 6.

M. tuberculosis strain-specific variation in sulfatase activity. Protein lysates were isolated from three distinct M. tuberculosis lineages: Indo-Oceanic, Euro-American, and East Asian. Lysates were resolved and imaged to reveal sulfatase activity. The three Indo-Oceanic samples, nos. 1833, 2311, and 1718, have bands that correspond to AtsD (Rv0633) and type III sulfatase (ZnSulf-B; Rv2407) activity. The Euro-American samples, nos. 0056, 0354, 3453, and 3253, all lack the highest AtsD band but have bands that match the pattern observed for AtsB (Rv3299). Two of the Euro-American samples, nos. 0056 and 0354, have the lowest band, corresponding to ZnSulf-B (Rv2407) activity. The East Asian strains, nos. 3244 and 2014, have bands corresponding to AtsD, AtsB, and ZnSulf-B activity.