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. 2013 Aug 12;8(8):e74012. doi: 10.1371/journal.pone.0074012

Table 1. Distribution of selected variables among cases and controls.

Alzheimer Controls P-value
Parameter Mean 95% C.I. Mean 95% C.I.
Folates (ng/ml) 6.2 1.8 6.8 1.2 N.S.
Homocysteine (μmol/l) 22.3 4.7 16.2 1.7 <0.01
Vitamin B12 (pg/ml) 401.3 78.2 404.9 73.5 N.S
MTHFR_C677T_wild_type (CC) 28% 14% 38% 16% N.S
MTHFR_C677T_heterozygous (CT) 40% 16% 47% 16% N.S
MTHFR_C677T_mutant (TT) 32% 15% 15% 12% N.S
MTHFR_A1298C_wild_type (AA) 45% 16% 60% 16% N.S
MTHFR_A1298C_heterozygous (AC) 55% 16% 40% 16% N.S
MTHFR_A1298C_mutant (CC) 0% 0% 0% 0% N.S
TYMS_28bp_wild_type (2R2R) 32% 15% 20% 13% N.S
TYMS_28bp_heterozygous (2R3R) 45% 16% 57% 16% N.S
TYMS_28bp_mutant (3R3R) 23% 14% 23% 14% N.S
TYMS_6bp_wild_type (+/+) 15% 12% 35% 15% N.S
TYMS_6bp_heterozygous (+/-) 57% 16% 53% 16% N.S
TYMS_6bp_mutant (-/-) 28% 14% 13% 11% N.S
MTRR_A66G_wild_type (AA) 23% 14% 25% 14% N.S
MTRR_A66G_heterozygous (AG) 43% 16% 52% 16% N.S
MTRR_A66G_mutant (GG) 35% 15% 23% 14% N.S
MTR_A2756G_wild_type (AA) 82% 12% 87% 11% N.S
MTR_A2756G_heterozygous (AG) 15% 12% 13% 11% N.S
MTR_A2756G_mutant (GG) 3% 5% 0% 0% N.S
RFC1_A80G_wild_type (AA) 22% 14% 10% 10% N.S
RFC1_A80G_heterozygous (AG) 60% 16% 62% 16% N.S
RFC1_A80G_mutant (GG) 18% 12% 28% 14% N.S
DNMT3B-149C>T_wild_type (CC) 45% 16% 50% 16% N.S
DNMT3B-149C>T_heterozygous (CT) 47% 16% 40% 16% N.S
DNMT3B-149C>T_mutant (TT) 8% 9% 10% 10% N.S
DNMT3B-5799G>T_wild_type (GG) 48% 16% 62% 16% N.S
DNMT3B-579G>T_heterozygous (GT) 47% 16% 28% 14% N.S
DNMT3B-5799C>T_mutant (TT) 5% 7% 10% 10% N.S