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. 2013 Aug 12;8(8):e72050. doi: 10.1371/journal.pone.0072050

Figure 4. Effect of Us3 kinase activity on HSV-1-specific antigen presentation.

Figure 4

B6MEFs (A) and MHC-I-/-MEFs (B) were infected with HSV-1(F), YK511 (Us3-K220M), YK513 (Us3-Repair) or YK591 (ΔICP47) at an MOI of 1 for 12 h and then co-cultured for an additional 12 h with lacZ-inducible CTL hybridoma cells recognizing HSV-1 gB (HSV-2.3.2E2), followed by β-galactosidase assays. Each data point is the mean ± standard error of triplicate samples, and is representative of three independent experiments.