Figure 7. Cardiac function in response to dobutamine was impaired in Pgam2 mice.

Cardiac function was analyzed by cardiac catheterization under dobutamine infusion. (A) Representative traces of left ventricular pressures. (B) Cardiac systolic function in response to dobutamine was impaired in Pgam2 mice. LVP: left ventricular systolic pressure; γ: μg/kg/min. A two-way repeated-measures ANOVA was used to test differences between groups in response to dobutamine infusion. Values are the mean ± SEM. *p<0.05, interaction of dobutamine doses with differences between Pgam2 mice and NTg mice (n = 10 for each group).