Table 2. Patient characteristics.
Patient | Age | Sex | Weight | Disease | Treatment | Bevacizumab at70 days (mg/L) |
1 | 78 | F | – | Breast cancer | Paclitaxel-bevacizumab | 93 |
2 | 60 | M | 64 | Glioma | Bevacizumab | 380* |
3 | 49 | F | 57 | Glioma | Irinotecan-bevacizumab | 252 |
4 | 58 | M | 75 | Glioma | Irinotecan-bevacizumab | 205 |
5 | 56 | M | 69 | Glioma | Irinotecan-bevacizumab | 229* |
6 | 52 | M | 79 | Glioma | Irinotecan-bevacizumab | 166 |
7 | 41 | M | – | Glioma | Irinotecan-bevacizumab | 283* |
8 | 50 | M | 74 | Glioma | Irinotecan-bevacizumab | 121* |
9 | 61 | M | 71 | Glioma | Bevacizumab | 313 |
10 | 56 | F | 102 | Breast cancer | Paclitaxel-bevacizumab | 131 |
11 | 59 | M | 63 | Glioma | Irinotecan-bevacizumab | 213 |
12 | 58 | M | – | Glioma | Irinotecan-bevacizumab | 289 |
13 | 53 | M | 79 | Glioma | Irinotecan-bevacizumab | 350 |
14 | 51 | F | 72 | Breast cancer | Paclitaxel-bevacizumab | 348 |
15 | 58 | M | 86 | Glioma | Irinotecan-bevacizumab | 355 |
16 | 56 | F | 82 | Glioma | Irinotecan-bevacizumab | 175 |
17 | 64 | M | 82 | Glioma | Irinotecan-bevacizumab | 267 |
Serum bevacizumab concentrations were determined at the plateau (70 days; values labeled with an asterisk correspond to 56 days). M: Male; F: Female.