Table 3.

Variable nucleotides in 2012 Texas isolates

(A) clade-specific non-synonymous mutations
Residue	JF488095	Clade I	JF920747	Clade II
C119	A	S	A	A
E123	T	N	T	T
NS1308	I	V	I	I
NS2A58	V	V	V	I
NS4B240	I	I	I	M

(B) population-specific non-synonymous mutations
	Clade I	Clade II	Clade I	Clade II
Residue	Dallas	Dallas	Montgomery	Montgomery
E12	L	L/V	L	L/V
E231	T/A	T	T	T
E367	A/V	A	A	A
E479	R/L	R	R	R
NS1105*	T	T/A	T	T
NS1349	Q	Q/R	Q	Q
NS2A52†	I	I/T	I/T	I/T
NS4A65	M	M/T	M	M
NS4A85	A	A/S	A	A
NS4B30	G/R	G	G	G
NS4B99	A	A/S	A	A
NS5587	A	A/V	A	A
NS5706	Y	Y/H	Y	Y
NS5866	E/G	E	E	E

(C) population-specific non-coding mutations
	Clade I	Clade II	Clade I	Clade II
Nucleotide	Dallas	Dallas	Montgomery	Montgomery
19	G	G/A	G/A	A
10407	T/G	T	T	T
10408	T	T/C	T	C
10429	A/G	A	A	A
10435	C	C/T	C	C
10448	T	T/G	T	T
10450	T	T/C	T	T
10563	A	A/G	A	A
10734	G	G/A	G	G
10774	C	C/T	C	C

^*ω < 1, P < 0.05.

^†ω > 1, P < 0.05.