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. 2013 Aug 12;8(8):e70196. doi: 10.1371/journal.pone.0070196

Figure 2. Increased peripheral lung fibrosis in cystic fibrosis (CF).

Figure 2

A) Histochemical staining for fibrosis (Masson trichrome stain, collagen shown in blue) in human normal lung (HNL), cystic fibrosis (CF) and idiopathic pulmonary fibrosis (IPF). Images are shown at approximately 100× from 2 separate HNL, CF and IPF specimens (bar = 250 µm). B) Comparison of collagen deposition (Masson trichrome stain) by semiquantitative analysis and C) quantitative morphometry. D) Correlation between quantitative morphometry (% collagen deposition) and semiquantitative analysis (1–5 scale).