Table 7. Top transcription factors by Ingenuity Pathway Analysis in non-IR scenario.

Transcription Regulator	p-value	Target molecules in dataset
CEBPA	2.11E-06	BTG2,CSF1R,DYNLT3,EPHX1,IFI27,MT2A,NFIL3,PFN2,PLOD2,RGS2 ,SERPINF1,SPINT2,SPP1 ,THBD,TUBB2A,VDR
VDR	5.39E-06	CDKN1A,IGFBP3,PLCG1,THBD,UCP2
SPDEF	5.78E-06	BIRC3,CD34,CDH11,COL4A2,COL4A6,COL5A2,CTGF,ITGA6,PLAU,SMAD1,TGFB1
MLL2	1.21E-05	CRIP1,CRIP2,ENO3,FHL1,GPR56,GPR64,NPR3
NR3C1	2.58E-05	AKTIP,BIRC3,CASP4,CDKN1A,CORO2A,CTNNBL1,CUL4A,GEM,IFIH1,IL6,ING1,NLRP10,PAK1,PAX3,PHF17,PLAGL1,POGK,PTGS2,RGS2,SDPR,SH3KBP1,SMAD1,SOX4,SPP1 ,STAT6,THBD,TNFAIP2,TNFRSF10A,TNFRSF11B,TNFRSF21,TRAF3IP2