Table 1.
Summary of the behavioral and neural characteristics of the fear retention and extinction systems in adult and infant (<P21) rodents.
| Adult rodent | Infant rodent | Infant rodents following early stress/CORT/FGF2 | |
|---|---|---|---|
| Renewal | ✓ | × | ✓ |
| Reinstatement | ✓ | × | ✓ |
| NMDA | ✓ | × | ? |
| GABA | ✓ | × | ✓ |
| Endogenous opioids | ✓ | ✓ | ? |
| Amygdala | ✓ | ✓ | ? |
| mPFC | ✓ | × | ? |
| Good fear retention | ✓ | × | ✓ |
✓Indicates that the phenomenon is present in age or treatment groups; × indicates that the phenomenon is absent in age or treatment groups; ? indicates that the phenomenon has not yet been examined in the age or treatment group. See text for definition of the terms used in this table.