Table 3.
The effect of surgical resection on clinical outcomes from cohort studies comparing drug resistant tuberculosis patients undergoing combination surgical resection and medical treatment vs. medical treatment alone
| Author | Country | Years | Cohort Size ( % having surgery) | MDRa/ XDRb | Analysis | Overall treatment success | Effect of Surgical Resection on Clinical Outcomes | |
|---|---|---|---|---|---|---|---|---|
| Univariate HRc (95% CI) | Multivariate HRc (95% CI) | |||||||
| Jeon 200947 | Korea | 2001–2005 | 176 (9%) | XDR | Predictors of poor outcomed | 18% | 0.08 (.02–0.28) | 0.18 (0.04–0.78) |
| Kwon 200848 | Korea | 1995–2004 | 155 (23%) | MDR XDR |
Predictors of favorable outcomee | 66% | - | 11.35 (3.02, 42.74) |
| Keshavjee 200858 | Russia | 2000–2004 | 608 (9%) | MDR XDR |
Predictors of favorable outcomee | 66% | 1.24 (0.69–2.26) | - f |
| KIm 200849 | Korea | 2000–2002 | 1407 (4%) | MDR XDR |
Predictors of favorable outcomee | 45% | 2.72 (1.56, 4.73) | 3.87 (1.69, 8.88) |
| Kim 200750 | Korea | 1996–2005 | 211 (30%) | MDR XDR |
Predictors of poor outcomed | 63% | 1.36 (0.70, 2.65) | - f |
| Torun 200759 | Turkey | 1992–2004 | 252 (26%) | MDR | Predictors of favorable outcomee | 77% | 1.7 (0.8–3.5) | 1.5 (0.64, 3.46) |
| Leimane 200555 | Latvia | 2000 | 204 (9%) | MDR | Predictors of poor outcomed | 66% | 0.3 (0.1–1.2) | -f |
| Chan 200453 | USA | 1984–1998 | 205 (63%) | MDR | Predictors of initial favorable responseg | 75% | 4.63 (1.89, 11.37) | 4.23 (1.28, 13.93) |