Table 2. Radiographic prognostic studies.
Marker | Year | Author | N | Data: univariate predictors | Multivariate |
---|---|---|---|---|---|
CT volume | 2012 | Gill (17) | 88 | Tumor volume predicts survival after EPP | Tumor volume, hgb, adjuvant therapy |
PET-CT | 2011 | Sharif (18) | 1108 | High SUV >10: ↓survival. Best evidence review 15 papers |
NA |
PET-CT volume | 2010 | Lee (19) | 13 | High MTV and TLG: ↓survival | MTV and TLG |
Quantitative FDG | 2010 | Nowak (20) | 89 | High TGV histology, weight loss, CT stage, EORTC prognostic score: ↓survival | TGV and weight loss for non-sarcomatoid |
PS, performance status; WBC, white blood cells; CRP, c-reactive protein; KPS, karnofsky performance status; EORTC, European Organization for Research and Treatment of Cancer; PFS, progression free survival; hgb, hemoglobin; EPP, extrapleural pneumonectomy; PD, pleurectomy/decortication; OS, overall survival; LDH, lactate dehydrogenase; PLT, platelet count; NA, not applicable; MTV, metabolic tumor volume; SUV, standardized uptake value; TLG, total lesion glycolysis; FDG, fluoro-D-glucose; TGV, total glycolytic volume