Figure 3.

Forest plot of the odds ratio (OR) of post-operative stroke in aortic arch surgery using deep hypothermic circulatory arrest alone (DHCA) or using moderate hypothermic circulatory arrest with selective antegrade cerebral protection (MHCA+SACP) as cerebral protection mechanisms. Misfeld et al. reported a mean of 22±2 °C as deep hypothermia. Exclusion of Misfeld et al. does not alter the overall significance of results (OR, 1.91, 95% CI, 1.23-2.97; P=0.004; I²=0%). The estimate of the OR of each trial corresponds to the middle of the squares, and the horizontal line shows the 95% confidence interval (CI). On each line, the number of events as a fraction of the total number randomized is shown for both treatment groups. For each subgroup, the sum of the statistics, along with the summary OR, is represented by the middle of the solid diamonds. A test of heterogeneity between the trials within a subgroup is given below the summary statistics. M-H, Mantel-Haenszel