Table 1. Demographic data of patients with chronic hepatitis C with and without occult HBV.
| Data | Occult HBV (+) (n = 18) | Occult HBV (-) (n = 32) | P value |
|---|---|---|---|
| Age, Mean ± SD, y | 29.88 ± 8.30 | 27.96 ± 8.41 | 0.44 |
| Sex, Male/Female | 13/5 | 21/11 | 0.75 |
| ALT(pre)a, Mean ± SD, IU/mL | 47.23 ± 32.17 | 70.77 ± 43.11 | 0.05 |
| AST(pre)a, Mean ± SD, IU/mL | 41.29 ± 25.28 | 84.41 ± 74.03 | 0.005c |
| ALKP(pre)a, Mean ± SD, IU/mL | 214.50 ± 88.62 | 316.45 ± 138.49 | 0.004c |
| ALT at 12 Weeksb,Mean ± SD, IU/mL | 32.37 ± 25.44 | 49.13 ± 33.14 | 0.08 |
| AST at 12 Weeksb,Mean ± SD, IU/mL | 36.44 ± 27.10 | 49.67 ± 35.22 | 0.19 |
| ALKP at 12 Weeksb,Mean ± SD, IU/mL | 292.44 ± 188.71 | 303.64 ± 125.24 | 0.81 |
| Duration of HCV Infection, Mean ± SD,y | 5.60 ± 3.72 | 6.32 ± 4.83 | 0.59 |
| Anti-HBc(+)/Total number (%) | 3/14 (21.4) | 7/27 (25.9) | 0.75 |
| HCV genotype (%) | |||
| 1b | 12 (70.6) | 20 (62.5) | 0.57 |
| 3b | 5(29.4) | 12 (37.5) | |
| HCV Viral Load,Mean ± SD, IU/mL | 8.79×105± 8.74×105 | 9.26×105± 10.10×105 | 0.87 |
| Histological Activity | |||
| Stage, Median (Min-Max) | 3.50(0-6) | 4.40(0-6) | 0.54 |
| Grade, Median (Min-Max) | 7.15(0-14) | 7.80(0-14) | 0.43 |
aAbbreviations: ALT, alanine transaminase; AST, aspartate aminotransferase; ALKP, Alkaline Phosphatase; Pre, Pretreatment
b12 weeks after starting therapies
cStatistically significant