Table 1.
PN defects in animals using lhIs35 marker.
| Genotype | No. of animals | No. of VD neurons | VD1/VD2 | Penetrance of the PN phenotype per cell typea |
VD12/13 | Penetranceb | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| VD3 | VD4 | VD5 | VD6 | VD7 | VD8 | VD9 | VD10 | VD11 | ||||||
| lhIs35 | 50 | 450 | N/D | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | N/D | 0.00 |
| lhIs36 | 53 | 477 | N/D | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | N/D | 0.00 |
| fmi-1 | 52 | 468 | N/D | 0.00 | 7..69 | 3.85 | 3.85 | 11.54 | 13.46 | 3.85 | 3.85 | 0.00 | N/D | 5.34 |
| lin-17 | 44 | 396 | N/D | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 4.55 | 4.55 | N/D | 1.01 |
| dsh-1 | 56 | 504 | N/D | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | N/D | 0.00 |
| prkl-1 c | 50 | 450 | N/D | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | N/D | 0.00 |
| vang-1 | 51 | 459 | N/D | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | N/D | 0.00 |
| dsh-1;fmi-1 | 60 | 540 | N/D | 13.33 | 33.33 | 13.33 | 13.33 | 6.67 | 6.67 | 8.33 | 10.00 | 1.67 | N/D | 11.85d |
(N/D): not determined.
All numbers are in percentage.
a
For example, number of defective VD3s/total number of VD3s scored.
b
Total number of defective VDs/total number of VDs scored.
c
lhIs36 marker was used to score PN defects in these animals.
d
Value different than fmi-1 animals by X2 test, p<0.01.