Table 4.

Association between total serum Vitamin D and other measures of Vitamin D status and risk of FibroSURE-ActiTest-determined advanced hepatic inflammatory activity (A2/A3 and A3) in male veterans with chronic hepatitis C infection.

	Univariate Models			Multivariate Model-Baseline^
	OR	95% CI	p-value	OR	95% CI	p- value
AFRICAN-AMERICAN (N=163)
Total Serum Vitamin D Category^
Deficient (< 12 ng/ml) or Insufficient (12–<20 ng/ml)	2.07	(1.01–4.27)	0.048	2.16	(0.98–4.79)	0.06
Normal (20 – 50 ng/ml)	1.0 (Ref)	-	-	1.0 (Ref)	-	-
High(>50 ng/ml)	0.81	(0.09–7.41)	0.85	1.43	(0.15–14.11)	0.76
WHITE (N=126)
Total Serum Vitamin D Category^
Deficient (< 12 ng/ml) or Insufficient (12–<20 ng/ml)	0.70	(25–2.01)	0.51	0.70	(0.23–2.18)	0.54
Normal (20 – 50 ng/ml)	1.0 (Ref)	-	-	1.0 (Ref)	-	-
High(>50 ng/ml)	1.27	(0.36–4.46)	0.71	0.73	(0.18–2.96)	0.66

^{^}All multivariate models including baseline model adjust for age, diabetic status, HCV viral load, chronic alcohol abuse, adiposity (BMI>25) and whether on prescribed vitamin D therapy on year prior to study enrollment.

^{^^^}Based on Institute of Medicine guidelines.

Abbreviation: CI, confidence interval; NCI-DHQ, National Cancer Institute Dietary History Questionnaire; OR, odds ratio.