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. 2013 Jun 27;14(7):13391–13402. doi: 10.3390/ijms140713391

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© 2013 by the authors; licensee MDPI, Basel, Switzerland

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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MPs-based transport of APODOX. (A) Micrographs of magnetic parties (1–unmodified MPs, 2–MPs modified by biotinylated apoferritin, 3–MPs modified by APODOX); (B) Scheme of the process–APODOX sample (No. 1) mixed with MPs, immobilized by magnetic field, unbound APODOX removed (No. 2), DOX released by pH decrease (No. 3), release of DOX from APODOX immobilized on MPs surface (No. 4); (C) Intensities of peaks (CE-LIF) in particular solution obtained during the procedure shown in panel (B); (D) Intensities of peaks (CE-LIF) in particular solution obtained during the procedure shown in panel (B) in 50% MeOH, for CE conditions see Figure 2.