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. 2013 Jun 28;14(7):13577–13591. doi: 10.3390/ijms140713577

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© 2013 by the authors; licensee MDPI, Basel, Switzerland

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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ZSTK474-reduced vascular endothelial growth factor (VEGF) inhibits tube formation by human umbilical vein endothelial cells (HUVECs). (A) Representative images depicting the tube formation by HUVEC following treatment with the conditioned media collected from PC3 cells after treatment with indicated concentrations of ZSTK474; (B) Percentage of the tube formation following treatment with the various conditioned media. Data are mean ± SD (n = 3), and are representative of three independent experiments.