Table 2.

Current and Potential use of Saliva/Oral fluid based Diagnostics

Current existing assays with active development of new detection systems	Potential use in near future
Pharmacological monitoring 11  Therapeutic drugs  Law enforcement applications   Drug intoxication   Illicit drugs   Forensics  Smoking exposure cotinine and thiocyanate  Steroid Hormones 4  Cortisol, estrogen, testosterone, and progesterone Infectious Diseases 35  Antibody testing: HIV, HCV and HBV  Antigen detection: Bacterial, Viral, Fungal DNA/RNA/Protein  Microorganism recovery: Bacterial, Viral, Fungal cultures	Autoimmune diseases 22;23   Autoantibodies: Sjögren’s syndrome   Allergic markers Cardiovascular diseases13   Acute myocardial infarction   Cardiac risk Cancer Screening and Diagnosis19;36–38  Oral cancer  Breast cancer  Cancer-specific markers Periodontal Diseases 20;39