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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Calcif Tissue Int. 2013 May 23;93(2):155–162. doi: 10.1007/s00223-013-9736-4

Figure 3.

Figure 3

Effects of Phex genotype on expression of Fgf23 in the femur and its target genes in the kidney. Values are presented by arbitrarily setting wild-type males as 1.0. Dark gray bars, males; light gray, females. Number of animals = 9-13 per group. The differences between five genotypic groups were significant for all measured parameters except Cyp27b1 (ANOVA p-values < 0.05). Differences between individual groups are indicated by superscript letters: Significant difference to same-sex littermate controls (+/Y vs. −/Y and +/+ vs. +/− or +/+)a, comparable male genotypes (+/Y vs. +/+ and −/Y vs. +/− or −/−)b, and heterozygous females (+/− vs. −/−)c by unpaired t-test (p-value < 0.05). All values are presented as mean ± SEM.