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Change in average daily frequency of moderate or severe hot flashes from baseline after 12 weeks of treatment relative to placebo
| Doses | BREEZE 1 | BREEZE 2 |
|---|---|---|
| 1,200 mg | −0.56 ± 0.42 (P = 0.1830) |
−1.56 ± 0.51 (P = 0.0024) |
| 1,800 mg | −1.53 ± 0.41 (P = 0.1975) |
−1.12 ± 0.51 (P = 0.0281) |
