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BREEZE 3 changes noted in frequency and severity score of moderate or severe hot flashes from baseline at 4 weeks and 12 weeks relative to placebo
| Doses | 4 Weeks | 12 Weeks |
|---|---|---|
| Frequency | −1.69 (P < 0.0001) |
−1.14 (P = 0.0007) |
| Severity | −0.21 (P < 0.0001) |
−0.19 (P = 0.0040) |
