TABLE 1.
Viral titers in the spleens of LCMV-clone 13-infected mice
| Group | LCMV titer (log10 PFU/spleen)a
|
|||
|---|---|---|---|---|
| Day 8 | Day 15 | Day 30 | Day 60 | |
| +/+ | 7.3 | 6.4 | 5.3 | 3.7 |
| 7.2 | 6.3 | 5.0 | <2.0 | |
| 7.8 | 6.3 | 5.6 | <2.0 | |
| p55−/− | 7.3 | 5.9 | 5.3 | 3.0 |
| 7.3 | 5.8 | 5.4 | 4.0 | |
| 7.7 | ND | ND | 3.9 | |
| p75−/− | 7.4 | 6.0 | 5.0 | <2.0 |
| 7.5 | 6.0 | 5.1 | <2.0 | |
| 7.6 | ND | 4.7 | <2.0 | |
| DKO | 7.4 | 6.1 | 5.3 | 2.0 |
| 7.6 | 5.9 | 5.0 | 5.0 | |
| 7.7 | 6.1 | 5.0 | 3.7 | |
a
Groups of +/+, p55−/−, p75−/−, and DKO mice were infected with LCMV-clone 13, and viral titers in the spleens were determined by a plaque assay on the indicated day after infection. The data are the viral titers of individual mice. ND, not done.