Table 3.
Effects of yohimbine on IMT performance
Measure (n=22) | Baseline | Maximum Change (Δ) | Univariate Effect Size for Δ | Repeated measures | |
---|---|---|---|---|---|
F (df) | P | ||||
Correct detections (%) | 82.1 ± 13.6 | −2.17 ± 8.27 | 0.262 | 1.47 (4,68) | 0.23 |
Commission errors (%) | 22.1 ± 14.4 | 2.64 ± 6.04 | 0.447 | 4.41 (4,76) | 0.003 |
Random errors (%) | 0.49 ± 0.99 | 0.61 ± 4.18 | 0.146 | 0.48 (4,80) | 0.75 |
Commission Errors/Corr. Detections | 0.276 ± 0.166 | 0.044 ± 0.103 | 0.427 | 2.64 (4,80) | 0.044 |
Reaction time, CD (msec) | 473 ± 83 | −42 ± 39 | −1.077 | 3.05 (4,80) | 0.022 |
Reaction time, CE (msec) | 477 ± 89 | −33 ± 55 | −0.600 | 3.53 (4,76) | 0.011 |
Discriminability | 0.873 ± 0.065 | −0.023 ± 0.065 | −0.354 | 0.78 (4,76) | 0.54 |
Response Bias | −0.083 ± 0.555 | −0.196 ± 0.422 | −0.465 | 3.02 (4,76) | 0.023 |
Means are given with standard deviations. Analyses for correct detections, commission errors, random errors, disciminability, and response bias used age and education as covariates; analyses of reaction times used age as covariate. Effect size (for Δ) is the effect size for the maximum difference between net change from baseline with administration of yohimbine versus placebo. Significant effects (p < 0.05) are shown in bold face.