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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Helicobacter. 2013 Apr 21;18(5):363–372. doi: 10.1111/hel.12055

Figure 3.

Figure 3

Time course of urease activation of H. pylori. H. pylori wildtype and ΔexbD strains were incubated in BHI, pH 5.5 or 7.4, for 30 to 180 min, and total urease activity was measured in the presence of the nonionic detergent C12E8 to bypass UreI. In the wildtype strain, there was a >3-fold increase in urease activity at pH 5.5 compared to that at pH 7.4 after 30 min, and it remained elevated for 3 h. The absence of ExbD had no effect on urease activity at pH 7.4 but abolished the increase in urease activity in acidic pH seen in the wildtype strain.