Neither spontaneous wheel running nor group housing improves hindlimb function following injections of 0.20 mg/mL EB (). (A) EB+RW mice displayed less severe deficits prior to assignment to experimental condition (i.e. EB+RW, single or multiple housed). (B) Difference scores (absolute value of week 1 BMS score – week 5 BMS score) similarly revealed no hindlimb recovery between EB-injected groups (B). Data are means ± SD, EB+RW, n=12; EB single, n=9; EB multiple, n=10; Saline, n=7.