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. 2013 Aug 13;8(8):e70964. doi: 10.1371/journal.pone.0070964

Table 1. Association analysis in the first-set screening samples (SNPs with nominal significant association).

				First-set screening										Second-set replication
Chr	SNP	closest GENE	BP^a	A1^b	A2^c	Phenotype^d	F_A^e	F_U^f	P^g	P_corrected	OR^h	SEⁱ	direc-tion^j	F_A	F_U	P^g	P_corrected	OR	SE	direction
1	rs472913	NF1A	61095558	G	C	BD	0.485	0.499	0.20	1	0.945	0.066	+
						SCZ	0.469		0.036	1	0.888	0.066	+
						Psychosis	0.477		0.063	1	0.916	0.058	+
3	rs2251219	PBRM1	52584787	A	G	BD	0.490	0.452	0.011	0.39	1.17	0.067	+	0.485	0.460	0.042	0.085	1.11	0.059	+
						SCZ	0.500		0.0018	0.064	1.21	0.066	+	0.489		0.0051	0.010	1.13	0.046	+
						Psychosis	0.495		0.0013	0.048	1.19	0.058	+	0.488		0.0035	0.0070	1.12	0.042	+
3	rs1042779	ITIH1	52821011	A	G	BD	0.498	0.465	0.025	0.92	1.14	0.067	+
						SCZ	0.503		0.012	0.43	1.16	0.066	+
						Psychosis	0.500		0.0076	0.28	1.15	0.058	+
3	rs736408	ITHI3	52835354	A	G	BD	0.450	0.480	0.034	1	0.885	0.067	+
						SCZ	0.446		0.021	0.75	0.874	0.066	+
						Psychosis	0.448		0.013	0.46	0.879	0.058	+
7	rs10240470	MADIL1	1916497	G	T	BD	0.107	0.085	0.014	0.49	1.29	0.11	+
						SCZ	0.098		0.090	1	1.17	0.11	+
						Psychosis	0.102		0.022	0.79	1.23	0.10	+
7	rs2709736	SP8	20862302	A	G	BD	0.305	0.345	0.0055	0.20	0.835	0.071	+
						SCZ	0.314		0.025	0.88	0.871	0.070	+
						Psychosis	0.310		0.0046	0.16	0.853	0.061	+
7	rs2709722	SP8	20867808	T	C	BD	0.311	0.350	0.0063	0.23	0.838	0.071	+	0.303	0.331	0.023	0.046	0.880	0.064	+
						SCZ	0.307		0.0024	0.085	0.820	0.070	+	0.314		0.049	0.098	0.922	0.049	+
						Psychosis	0.309		0.0010	0.037	0.829	0.061	+	0.311		0.017	0.033	0.909	0.045	+
10	rs10994336	ANK3	62179812	T	C	BD	0.362	0.346	0.16	1	1.07	0.070	+
						SCZ	0.380		0.017	0.62	1.16	0.069	+
						Psychosis	0.371		0.036	1	1.11	0.060	+

a: BP: base position based upon hg19.

b: A1: minor allele based upon whole sample.

c: A2: major allele.

d: BD: bipolar disorder, SCZ: schizophrenia.

e: F_A: Frequency of A1 in affected subjects.

f: F_U: Frequency of A1 in unaffected subjects.

g: P values based upon one-tailed test.

h: OR: Odds ratio for A1 (i.e. A2 is reference).

i: SE: standard error.

j: direction: direction of the effect size based upon the original studies. +: same direction. −: opposite direction.